Experimental Study of the Efficacy of Pharmaconutrient Enteral Nutrition and Inulin in the Correction of Intestinal Motor Disorders and Microbiocenosis in the Postoperative Period Under Endotoxemia Conditions-Reference-Cited by-同舟云学术

Experimental Study of the Efficacy of Pharmaconutrient Enteral Nutrition and Inulin in the Correction of Intestinal Motor Disorders and Microbiocenosis in the Postoperative Period Under Endotoxemia Conditions

Published:2023-11-20 Issue:3E Volume:19 Page:71-76
ISSN:2713-0428
Container-title:Journal Biomed
language:
Short-container-title:BIOMEDICINE

Author:

Tropskaya N. S.¹,Kislyаkova E. A.²,Vilkova I. G.²,Gurman Yu. V.²,Kislitsyna O. S.²,Borodina Ye. N.²,Chernen’kaya T. V.²,Popova T. S.²

Affiliation:

1. N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Department; Moscow Aviation Institute (National Research University)

2. N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Department

Abstract

A scheme for correcting intestinal motor disorders and microbiocenosis is proposed. Experiments on rats included a sequential jejunum administration of pharmaconutrient enteral nutrition (Intestamine, containing glutamine and tributyrin) and inulin, a prebiotic preparation. The application of this scheme in the postoperative period in the setting of endotoxemia prevents excessive bacterial growth in the jejunum, stimulates the appearance of propulsive peristalsis, eliminates pathological motility patterns and promotes early recovery of coordinated peristalsis of the small intestine.

Publisher

Scientific Center for Biomedical Technologies of the Federal Medical-Biological Agency

Subject

General Medicine

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