Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world

Author:

Ebenezer ThankGod Echezona1ORCID,Low Ross S.2ORCID,O'Neill Ellis Charles3ORCID,Huang Ishuo4ORCID,DeSimone Antonio5ORCID,Farrow Scott C.67ORCID,Field Robert A.8ORCID,Ginger Michael L.9ORCID,Guerrero Sergio Adrián10ORCID,Hammond Michael11ORCID,Hampl Vladimír1213ORCID,Horst Geoff14ORCID,Ishikawa Takahiro15ORCID,Karnkowska Anna1617ORCID,Linton Eric W.18ORCID,Myler Peter19ORCID,Nakazawa Masami20ORCID,Cardol Pierre21ORCID,Sánchez-Thomas Rosina22ORCID,Saville Barry J.23ORCID,Shah Mahfuzur R.6ORCID,Simpson Alastair G. B.24ORCID,Sur Aakash19ORCID,Suzuki Kengo25,Tyler Kevin M.2627ORCID,Zimba Paul V.2829ORCID,Hall Neil230ORCID,Field Mark C.1131ORCID

Affiliation:

1. European Bioinformatics Institute 1 European Molecular Biology Laboratory , , Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD , UK

2. Organisms and Ecosystems, Earlham Institute, Norwich Research Park 2 , Norwich NR4 7UZ , UK

3. School of Chemistry, University of Nottingham 3 , Nottingham NG7 2RD , UK

4. United States Food and Drug Administration, Center for Food Safety and Applied Nutrition 4 Office of Regulatory Science , , College Park, MD 20740 , USA

5. The BioRobotics Institute, Scuola Superiore Sant'Anna 5 , Pisa 56127 , Italy

6. Noblegen Inc. 6 Discovery Biology , , Peterborough, Ontario K9L 1Z8 , Canada

7. Trent University 7 Environmental and Life Sciences Graduate Program , , Peterborough, Ontario K9L 0G2 , Canada

8. Department of Chemistry and Manchester Institute of Biotechnology, University of Manchester 8 , Manchester M1 7DN , UK

9. School of Applied Sciences, University of Huddersfield 9 , Huddersfield HD1 3DH , UK

10. Laboratorio de Enzimología Molecular, Instituto de Agrobiotecnología del Litoral. CCT CONICET Santa Fe 10 , Santa Fe 3000 , Argentina

11. Institute of Parasitology, Biology Centre, Czech Academy of Sciences 11 , České Budějovice 370 05 , Czech Republic

12. Charles University 12 , Faculty of Science, Department of Parasitology , , Vestec 25250 , Czech Republic

13. BIOCEV 12 , Faculty of Science, Department of Parasitology , , Vestec 25250 , Czech Republic

14. Kemin Industries, Research and Development 13 , Plymouth, MI 48170 , USA

15. Institute of Agricultural and Life Sciences, Academic Assembly, Shimane University 14 , Matsue 690-8504 , Japan

16. Institute of Evolutionary Biology 15 , Faculty of Biology , , Warsaw 02-089 , Poland

17. University of Warsaw 15 , Faculty of Biology , , Warsaw 02-089 , Poland

18. Central Michigan University 16 Department of Biology , , Mt. Pleasant, MI 48859 , USA

19. Center for Global Infectious Disease Research, Seattle Children's Research Institute and Department of Biomedical Informatics & Medical Education, University of Washington 17 , WA 98109 , USA

20. Department of Applied Biochemistry, Faculty of Agriculture, Osaka Metropolitan University 18 , Sakai, Osaka, 599-8531 , Japan

21. Department of Life Sciences, Institut de Botanique, Université de Liège 19 , Liège 4000 , Belgium

22. Instituto Nacional de Cardiología, Ignacio Chávez 20 , Mexico 14080 , Mexico

23. Forensic Science, Environmental and Life Sciences Graduate Program, Trent University 21 , Peterborough K9L 0G2 , Canada

24. Dalhousie University 22 Department of Biology and Institute for Comparative Genomics , , Halifax, Nova Scotia B3H 4R2 , Canada

25. R&D Company, Euglena Co., Ltd., 2F Yokohama Bio Industry Center (YBIC), 1-6 Suehiro, Tsurumi, Yokohama 23 , Kanagawa, 230-0045 , Japan

26. Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich Research Park 24 , Norwich NR4 7TJ , UK

27. King Abdul Aziz University 25 Center of Excellence for Bionanoscience Research , , Jeddah , Saudi Arabia

28. PVZimba, LLC 26 , 12241 Percival St, Chester, VA 23831 , USA

29. Rice Rivers Center, VA Commonwealth University 27 , Richmond, VA 23284 , USA

30. School of Biological Sciences, University of East Anglia 28 , Norwich, NR4 7TJ, Norfolk , UK

31. School of Life Sciences, University of Dundee 29 , Dundee DD1 5EH , UK

Abstract

ABSTRACT Euglenoids (Euglenida) are unicellular flagellates possessing exceptionally wide geographical and ecological distribution. Euglenoids combine a biotechnological potential with a unique position in the eukaryotic tree of life. In large part these microbes owe this success to diverse genetics including secondary endosymbiosis and likely additional sources of genes. Multiple euglenoid species have translational applications and show great promise in production of biofuels, nutraceuticals, bioremediation, cancer treatments and more exotically as robotics design simulators. An absence of reference genomes currently limits these applications, including development of efficient tools for identification of critical factors in regulation, growth or optimization of metabolic pathways. The Euglena International Network (EIN) seeks to provide a forum to overcome these challenges. EIN has agreed specific goals, mobilized scientists, established a clear roadmap (Grand Challenges), connected academic and industry stakeholders and is currently formulating policy and partnership principles to propel these efforts in a coordinated and efficient manner.

Publisher

The Company of Biologists

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

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