Affiliation:
1. Neural Stem Cell Institute, 1 Discovery Drive, Rensselaer, NY 12144, USA
Abstract
Retinal degenerative diseases are the leading causes of blindness worldwide. Replacing lost retinal cells via stem cell-based therapies is an exciting, rapidly advancing area of translational research that has already entered the clinic. Here, we review the status of these clinical efforts for several significant retinal diseases, describe the challenges involved and discuss how basic developmental studies have contributed to and are needed to advance clinical goals.
Funder
New York State Empire Stem Cell Fund
National Eye Institute
Macula Vision Research Foundation
Neural Stem Cell Institute Regenerative Research Foundation
Publisher
The Company of Biologists
Subject
Developmental Biology,Molecular Biology
Cited by
38 articles.
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