1. University of Milan 1 Department of Pharmacological and Biomolecular Sciences , , Milan 20133 , Italy
2. CRC Aldo Ravelli for Neurotechnology and Experimental Brain Therapeutics 2 , Department of Health Sciences , , Milan 20142 , Italy
3. University of Milan 2 , Department of Health Sciences , , Milan 20142 , Italy
4. University of Milan 3 Department of Health Sciences , , Milan 20142 , Italy
5. Laboratory of Endocrine and Metabolic Research, IRCCS Istituto Auxologico Italiano 4 , Cusano Milanino 20095 , Italy
6. Unité Fonctionnelle Innovation en Diagnostic Génomique des Maladies Rares, Fédération Hospitalo-Universitaire (FHU) TRANSLAD, CHU Dijon Bourgogne 5 , Dijon 21079 , France
7. INSERM UMR 1231 GAD (Génétique des Anomalies du Développement), Université de Bourgogne 6 , Dijon 21070 , France
8. Centre Hospitalier de l'Estran 7 Genetics and Neurodevelopment , , Pontorson 50170 , France
9. Centre for Endocrinology William Harvey Research Institute Barts and the London School of Medicine and Dentistry, Queen Mary University of London 8 , London EC1M 6BQ , UK
10. Royal London Children's Hospital, Barts Health NHS Trust 9 , London E1 1BB , UK
11. Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre 10 , Cambridge CB2 0AW , UK
12. Biozentrum of the University of Basel 11 , Basel 4056 , Switzerland