Abstract
Primordial germ cells (PGCs) are the precursors of gametes, and a presumptive PGC-like cell (PGCLC) population was recently identified in mouse gastruloids. A new paper in Development investigates this population in detail and offers new insight into the signals that contribute to PGC specification and maturation. To hear more about the story, we caught up with first author Christopher Cooke and corresponding author Naomi Moris, Group Leader at the Francis Crick Institute, UK.
Publisher
The Company of Biologists
Subject
Developmental Biology,Molecular Biology