BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells
Author:
Affiliation:
1. Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Biomedical Sciences Building, University Walk, University of Bristol, BS8 1TD, UK
2. Hadyn Ellis Building, Maindy Road, Cathays, Cardiff, CF24 4HQ, UK
Abstract
Funder
Bowel and Cancer Research
Cancer Research UK
Wellcome Trust
Medical Research Council
Publisher
The Company of Biologists
Subject
General Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology (miscellaneous),Medicine (miscellaneous),Neuroscience (miscellaneous)
Link
http://journals.biologists.com/dmm/article-pdf/doi/10.1242/dmm.037697/1863381/dmm037697.pdf
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3. Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors;Ashley;Cancer Res.,2013
4. Identification of stem cells in small intestine and colon by marker gene Lgr5;Barker;Nature,2007
5. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro;Barker;Cell Stem Cell,2010
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