Neural Activation and Transformation in Explants of Competent Ectoderm under the Influence of Fragments of Anterior Notochord in Urodeles

Author:

Nieuwkoop P. D.1,Nigtevecht G. v.1

Affiliation:

1. Hubrecht Laboratory, Utrecht

Abstract

Experiments in which folds of competent ectoderm were attached to neural plates of host embryos at various cranio-caudal levels (Nieuwkoop et al., 1952) suggested that two successive influences emanate from the underlying archenteron roof: a first one representing a more or less non-specific activation which leads autonomously to a differentiation in a prosencephalic direction; and a second one transforming these prosencephalic differentiation tendencies into more caudal ones leading to the formation of rhombencephalon and spinal cord. The work of Eyal-Giladi (1954) in which the temporal and spatial relations of neural induction were analysed by means of an interruption of the induction at various stages of development and at various cranio-caudal levels of the presumptive neural area showed very clearly that during gastrulation two successive waves of induction actually pass through the presumptive neuro-ectoderm in a caudo-cranial direction. The first wave, which emanates from the presumptive prechordal material, leads to an activation of the ectoderm and its autonomous development in a prosencephalic direction.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3