1. Keio University 1 Department of Biosciences and Informatics, Faculty of Science and Technology , , Kouhoku-ku, Yokohama 223-8522 , Japan
2. Institute of Science and Technology Austria 2 , Klosterneuburg , 3400, Austria
3. Waseda Research Institute for Science and Engineering, Waseda University 3 , 2-2 Wakamatsucho, Shinjuku, Tokyo 162-8480 , Japan
4. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University 4 , Kaohsiung City 80708 , Taiwan