eNOS at a glance

Author:

Sessa William C.1

Affiliation:

1. Department of Pharmacology and Vascular Cell Signaling Program, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, CT 06536, USA

Publisher

The Company of Biologists

Subject

Cell Biology

Reference27 articles.

1. Boo, Y. C. and Jo, H. (2003). Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. Am. J. Physiol. Cell Physiol.285, C499-C508.

2. Chen, Z. P., Mitchelhill, K. I., Michell, B. J., Stapleton, D., Rodriguez-Crespo, I., Witters, L. A., Power, D. A., Ortiz de Montellano, P. R. and Kemp, B. E. (1999). AMP-activated protein kinase phosphorylation of endothelial NO synthase. FEBS Lett.443, 285-289.

3. Dimmeler, S., Fissthaler, B., Fleming, I., Assmus, B., Hermann, C. and Zeiher, A. (1998). Shear stress stimulates the protein kinase Akt-involvement in the regulation of endothelial nitric oxide synthase. Circulation98, I-312.

4. Feil, R., Lohmann, S. M., de Jonge, H., Walter, U. and Hofmann, F. (2003). Cyclic GMP-dependent protein kinases and the cardiovascular system: insights from genetically modified mice. Circ. Res.93, 907-916.

5. Fleming, I., Fisslthaler, B., Dimmeler, S., Kemp, B. E. and Busse, R. (2001). Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. Circ. Res.88, E68-E75.

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