1. University of California Davis 1 , Department of Molecular and Cellular Biology, Davis, CA 95616 , USA
2. University of Michigan 2 Department of Molecular & Integrative Physiology , , Ann Arbor, MI 48109 , USA
3. Institute of Gerontology, Geriatrics Center, University of Michigan 3 , Ann Arbor, MI 48109 , USA
4. University of California, San Francisco 4 Deptartment of Biochemistry & Biophysics , , 600 16th Street, San Francisco, CA 94158 , USA
5. Institute of Developmental & Regenerative Medicine (IDRM) 5 , Department of Physiology, Anatomy & Genetics, IMS-Tetsuya Nakamura Building, Old Road Campus, Roosevelt Drive, Headington, Oxford OX3 7TY , UK
6. The University of Tokyo 6 Graduate School of Pharmaceutical Sciences , , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 , Japan