A dual role for 7-dehydrocholesterol reductase in regulating Hedgehog signalling?
Author:
Affiliation:
1. Center for Experimental and Molecular Medicine, Academic Medical Center,Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Publisher
The Company of Biologists
Subject
Developmental Biology,Molecular Biology
Link
http://journals.biologists.com/dev/article-pdf/133/20/3951/1153791/3951.pdf
Reference3 articles.
1. Bijlsma, M. F., Spek, C. A., Zivkovic, D., Van de Water, S.,Rezaee, F. and Peppelenbosch, M. P. (2006). Repression of Smoothened by Patched-dependent (pro-)vitamin D3 secretion. PLoS Biol.4,e232
2. Cooper, M. K., Wassif, C. A., Krakowiak, P. A., Taipale, J.,Gong, R., Kelley, R. I., Porter, F. D. and Beachy, P. A.(2003). A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis. Nat. Genet.33,508-513.
3. Koide, T., Hayata, T. and Cho, K. W. (2006). Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Development133,2395-2405.
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