The roles of receptor and ligand endocytosis in regulating Notch signaling-Reference-Cited by-同舟云学术

The roles of receptor and ligand endocytosis in regulating Notch signaling

Published:2005-04-15 Issue:8 Volume:132 Page:1751-1762
ISSN:1477-9129
Container-title:Development
language:en
Short-container-title:

Author:

Le Borgne Roland¹,Bardin Allison¹,Schweisguth François¹

Affiliation:

1. CNRS UMR 8542, Ecole Normale Supérieure, 46, rue d'Ulm 75230 Paris cedex, France

Abstract

Cell-cell signaling is a central process in the formation of multicellular organisms. Notch (N) is the receptor of a conserved signaling pathway that regulates numerous developmental decisions, and the misregulation of N has been linked to various physiological and developmental disorders. The endocytosis of N and its ligands is a key mechanism by which N-mediated cell-cell signaling is developmentally regulated. We review here the recent findings that have highlighted the importance and complexity of this regulation.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Link

http://journals.biologists.com/dev/article-pdf/132/8/1751/1544006/1751.pdf

Reference112 articles.

1. Aguilar, R. C. and Wendland, B. (2005). Endocytosis of membrane receptors: two pathways are better than one. Proc. Natl. Acad. Sci. USA102,2679-2680.

2. Aho, S. (2004). Soluble form of Jagged1: unique product of epithelial keratinocytes and a regulator of keratinocyte differentiation. J. Cell. Biochem.92,1271-1281.

3. Ben-Yaacov, S., Le Borgne, R., Abramson, I., Schweisguth, F. and Schejter, E. D. (2001). Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling. J. Cell Biol.152, 1-13.

4. Berdnik, D., Torok, T., Gonzalez-Gaitan, M. and Knoblich, J.(2002). The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev. Cell3,221-231.

5. Bingham, S., Chaudhari, S., Vanderlaan, G., Itoh, M., Chitnis,A. and Chandrasekhar, A. (2003). Neurogenic phenotype of mind bomb mutants leads to severe patterning defects in the zebrafish hindbrain. Dev. Dyn.228,451-463.

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