Electron Microscopic Study of Penetration of Newcastle Disease Virus into Cells Leading to Formation of Polykaryocytes-Reference-Cited by-同舟云学术

Electron Microscopic Study of Penetration of Newcastle Disease Virus into Cells Leading to Formation of Polykaryocytes

Published:1967-03-01 Issue:1 Volume:2 Page:71-76
ISSN:1477-9137
Container-title:Journal of Cell Science
language:en
Short-container-title:

Author:

MEISELMAN N.¹,KOHN A.²,DANON D.²

Affiliation:

1. The Weizmann Institute of Science, Rehovoth, and The Israel Institute for Biological Research, Ness Ziona, Israel; Permanent address: C.W. Post College of Long Island University, Greenvale, N.Y. 11548, U.S.A.

2. The Weizmann Institute of Science, Rehovoth, and The Israel Institute for Biological Research, Ness Ziona, Israel

Abstract

Treatment of FL or Lu 106 epithelial cells with Newcastle disease virus (NDV) at an input multiplicity of 500 EID50 per cell induces in these cells the formation of polykaryocytes at the end of 2-3 h of contact. Electron micrographs of such NDV-treated monolayers after 2-10 min of incubation show the presence of virions adsorbed to the cell membranes, in vacuoles and with the viral envelope partly fused with the cell membrane. In polykaryocytes induced by NDV, remnants of cell membranes showing numerous breaks may still be present after 3 h.

Publisher

The Company of Biologists

Subject

Cell Biology

Link

http://journals.biologists.com/jcs/article-pdf/2/1/71/1424534/71.pdf

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Newcastle Disease Virus Replication;Newcastle Disease;1988

2. Changes Induced in Cell Membranes Adsorbing Animal Viruses, Bacteriophages, and Colicins;Modern Aspects of Electrochemistry;1983

3. Macrophage Polykarya;CRC Critical Reviews in Toxicology;1979-01

4. Early Interactions of Viruses With Cellular Membranes;Advances in Virus Research Volume 24;1979

5. Studies on Membrane Fusion with Natural and Model Membranes;Methods in Membrane Biology;1979