The cell biology behind the oncogenic PIP3 lipids-Reference-Cited by-同舟云学术

The cell biology behind the oncogenic PIP3 lipids

Published:2019-01-01 Issue:1 Volume:132 Page:
ISSN:1477-9137
Container-title:Journal of Cell Science
language:en
Short-container-title:

Author:

Carrera Ana C.¹,Anderson Richard²

Affiliation:

1. Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Darwin 3, Madrid 28049, Spain

2. University of Wisconsin School of Medicine and Public Health, 1300 University Avenue, Madison, WI 53706-1532, USA

Abstract

ABSTRACT The different mechanisms of phosphoinositide 3-kinase (PI3K) activation in cancer as well as the events that result in PI3K pathway reactivation after patient treatment with PI3K inhibitors was discussed on October 15–17th, 2018, in the medieval town of Baeza (Universidad Internacional de Andalucía, Spain) at the workshop entitled ‘The cell biology behind the oncogenic PIP3 lipids’. These topics and the data presented regarding cellular functions altered by PI3K deregulation, the cooperation of PI3K/PTEN mutations with other tumor drivers, and the lessons learned for PI3K-targeted therapy, are discussed below.

Funder

Biochemical Journal

Company of Biologists

Ministerio de Ciencia e Innovación

Madrid regional government

Fundación Ramón Areces

Fundación Científica Asociación Española Contra el Cáncer

Publisher

The Company of Biologists

Subject

Cell Biology

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