1. Department of Systems Biology, Harvard Medical School, Boston MA 02115,USA
2. Five Prime Therapeutics, South San Francisco CA 94080, USA
3. Howard Hughes Medical Institute, Developmental Genetics Program, Skirball Institute and Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA
4. Department of Molecular, Cell and Developmental Biology, Sinsheimer Laboratory, University of Santa Cruz, Santa Cruz, CA 95064, USA