Affiliation:
1. Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, Tennis Court Road, Cambridge CB2 1QN, UK
Abstract
It is relatively unusual for the Nobel Prize in Physiology or Medicine to be made, to a large extent, on the basis of a single author paper, published over 50 years ago, for work carried out by a graduate student. This was largely true of a paper published in 1962 in the journal Development (called at that time the Journal of Embryology and Experimental Morphology). The main subject of that paper was the production of normal tadpoles from the nuclei of intestinal epithelium cells of Xenopus laevis. In view of this unusual situation, I have been invited to comment on the 1962 paper.
Publisher
The Company of Biologists
Subject
Developmental Biology,Molecular Biology
Reference7 articles.
1. Transplantation of living nuclei from blastula cells into enucleated frogs' eggs;Briggs;Proc. Natl. Acad. Sci. USA,1952
2. Development and cellular differentiation of neural nuclear-transplants of known karyotype;Di Berardino;Dev. Biol.,1967
3. A description of the technique for nuclear transplantation in Xenopus laevis;Elsdale;J. Embryol. Exp. Morphol.,1960
4. The developmental capacity of nuclei taken from differentiating endoderm cells of Xenopus laevis;Gurdon;J. Embryol. Exp. Morphol,1960
5. The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles;Gurdon;J. Embryol. Exp. Morphol.,1962
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