1. Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg 1 , Albertstrasse 25, D-79104 Freiburg , Germany
2. Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg 2 , Albertstrasse 19a, D-79104 Freiburg , Germany
3. University of Freiburg 3 Faculty of Biology , , Schänzlestrasse 1, D-79104 Freiburg , Germany
4. Signaling Research Centers BIOSS and CIBSS, University of Freiburg 4 , Schänzlestrasse 18, D-79104 Freiburg , Germany