Affiliation:
1. Johns Hopkins University School of Medicine HHMI and Department of Molecular Biology and Genetics , , Baltimore, MD 21205 , USA
Abstract
ABSTRACT
A hallmark of all germ cells is the presence of germ granules: assemblies of proteins and RNA that lack a delineating membrane and are proposed to form via condensation. Germ granules across organisms share several conserved components, including factors required for germ cell fate determination and maintenance, and are thought to be linked to germ cell development. The molecular functions of germ granules, however, remain incompletely understood. In this Development at a Glance article, we survey germ granules across organisms and developmental stages, and highlight emerging themes regarding granule regulation, dynamics and proposed functions.
Funder
National Institutes of Health
Publisher
The Company of Biologists
Subject
Developmental Biology,Molecular Biology
Cited by
5 articles.
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