Affiliation:
1. Institute of Human Genetics, CNRS, 141, rue de la Cardonille, 34396 Montpellier Cédex 5, France.
Abstract
The epigenetic regulation of chromatin structure and composition has often been studied molecularly in the context of specific DNA-dependent processes. However, epigenetics also play important global roles in shaping and maintaining cell identity, and in patterning the body plan during normal development. Moreover, alterations in epigenetic regulation are involved in many diseases, including cancer. The advances in our understanding of the impact of epigenetics in development and disease were discussed at a recent Keystone symposium.
Publisher
The Company of Biologists
Subject
Developmental Biology,Molecular Biology
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