The ABC of the BX-C: the bithorax complex explained

Author:

Maeda Robert K.1,Karch François1

Affiliation:

1. Department of Zoology and Animal Biology and National Research Centre`Frontiers in Genetics', University of Geneva, 30 quai E. Ansermet, 1211 Geneva-4, Switzerland.

Abstract

As one of two Drosophila Hox clusters, the bithorax complex (BX-C)is responsible for determining the posterior thorax and each abdominal segment of the fly. Through the dissection of its large cis-regulatory region,biologists have obtained a wealth of knowledge that has informed our understanding of gene expression, chromatin dynamics and gene evolution. This primer attempts to distill and explain our current knowledge about this classic, complex locus.

Publisher

The Company of Biologists

Subject

Developmental Biology,Molecular Biology

Reference112 articles.

1. Barges, S., Mihaly, J., Galloni, M., Hagstrom, K., Müller,M., Shanower, G., Schedl, P., Gyurkovics, H. and Karch, F.(2000). The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain. Development127,779-790.

2. Bateson, W. (1894). Materials for the Study of Variation. London: Macmillan.

3. Beachy, P. A., Helfand, S. L. and Hogness, D. S.(1985). Segmental distribution of bithorax complex proteins during Drosophila development. Nature313,545-551.

4. Bender, W. and Hudson, A. (2000). P element homing to the Drosophila bithorax complex. Development127,3981-3992.

5. Bender, W. and Fitzgerald, D. P. (2002). Transcription activates repressed domains in the Drosophila bithorax complex. Development129,4923-4930.

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