Integrins and cell proliferation-Reference-Cited by-同舟云学术

Integrins and cell proliferation

Published:2001-07-15 Issue:14 Volume:114 Page:2553-2560
ISSN:1477-9137
Container-title:Journal of Cell Science
language:en
Short-container-title:

Author:

Schwartz Martin Alexander¹²,Assoian Richard K.³

Affiliation:

1. Department of Vascular Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA

2. Author for correspondence (e-mail: schwartz@scripps.edu )

3. Department of Pharmacology, University of Pennsylvania School of Medicine, 3620 Hamilton Walk, Philadelphia, PA 19104, USA

Abstract

Cell cycle progression in mammalian cells is strictly regulated by both integrin-mediated adhesion to the extracellular matrix and by binding of growth factors to their receptors. This regulation is mediated by G1 phase cyclin-dependent kinases (CDKs), which are downstream of signaling pathways under the integrated control of both integrins and growth factor receptors. Recent advances demonstrate a surprisingly diverse array of integrin-dependent signals that are channeled into the regulation of the G1 phase CDKs. Regulation of cyclin D1 by the ERK pathway may provide a paradigm for understanding how cell adhesion can determine cell cycle progression.

Publisher

The Company of Biologists

Subject

Cell Biology

Link

http://journals.biologists.com/jcs/article-pdf/114/14/2553/1356670/2553.pdf

Reference92 articles.

1. Adams, J. C. and Watt, F. M. (1993). Regulation of development and differentiation by the extracellular matrix. Development117, 1183-1198.

2. Adnane, J., Bizouarn, F. A., Qian, Y., Hamilton, A. D. and Sebti, S. M. (1998). p21(WAF1/CIP1) is upregulated by the geranylgeranyltransferase I inhibitor GGTI-298 through a transforming growth factor beta- and Sp1-responsive element: involvement of the small GTPase rhoA. Mol. Cell. Biol.18, 6962-6970.

3. Baron, V. and Schwartz, M. (2001). Cell adhesion regulates ubiquitin-mediated degradation of the platelet derived growth factor β. J. Biol. Chem. (in press).

4. Berberis, L., Wary, K. K., Fiucci, G., Liu, F., Hirsch, E., Brancaccio, M., ALtruda, F., Tarone, G. and Giancotti, F. G. (2000). Distinct roles for the adapter protein Shc and focal adhesion kinase in integrin signaling to Erk. J. Biol. Chem. (in press).

5. Bohmer, R. M., Scharf, E. and Assoian, R. K. (1996). Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1. Mol. Biol. Cell7, 101-111.

Cited by 270 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Integrating integrins with the hallmarks of cancer;Matrix Biology;2024-06

2. Arp2/3 complex-dependent actin regulation protects the survival of tissue-resident mast cells;2024-02-25

3. Highly Aligned Ternary Nanofiber Matrices Loaded with MXene Expedite Regeneration of Volumetric Muscle Loss;Nano-Micro Letters;2024-01-04

4. Associating growth factor secretions and transcriptomes of single cells in nanovials using SEC-seq;Nature Nanotechnology;2023-12-11

5. Differential modulation of cellular phenotype and drug sensitivity by extracellular matrix proteins in primary and metastatic pancreatic cancer cells;Molecular Biology of the Cell;2023-12-01