One hundred years of Drosophila cancer research: no longer in solitude-Reference-Cited by-同舟云学术

One hundred years of Drosophila cancer research: no longer in solitude

Published:2019-04-01 Issue:4 Volume:12 Page:
ISSN:1754-8411
Container-title:Disease Models & Mechanisms
language:en
Short-container-title:

Author:

Villegas Santiago Nahuel¹^ORCID

Affiliation:

1. Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad Miguel Hernandez (UMH), Campus de Sant Joan, Apartado 18, 03550 Sant Joan, Alicante, Spain

Abstract

ABSTRACT When Mary Stark first described the presence of tumours in the fruit fly Drosophila melanogaster in 1918, would she ever have imagined that flies would become an invaluable organism for modelling and understanding oncogenesis? And if so, would she have expected it to take 100 years for this model to be fully accredited? This Special Article summarises the efforts and achievements of Drosophilists to establish the fly as a valid model in cancer research through different scientific periods.

Funder

Ministerio de Economía y Competitividad

Agencia Estatal de Investigación

Fundación Científica Asociación Española Contra el Cáncer

Publisher

The Company of Biologists

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology (miscellaneous),Medicine (miscellaneous),Neuroscience (miscellaneous)

Link

http://journals.biologists.com/dmm/article-pdf/doi/10.1242/dmm.039032/1863611/dmm039032.pdf

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