Loss of Tropomodulin4 in the zebrafish mutant träge causes cytoplasmic rod formation and muscle weakness reminiscent of nemaline myopathy
Author:
Affiliation:
1. ARMI, Monash University, Clayton, VIC, Australia;
2. Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, SE 17177, Sweden;
3. University of Queensland, St Lucia, QLD, Australia
Abstract
Publisher
The Company of Biologists
Subject
General Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology (miscellaneous),Medicine (miscellaneous),Neuroscience (miscellaneous)
Link
http://journals.biologists.com/dmm/article-pdf/7/12/1407/1866663/1407.pdf
Reference36 articles.
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2. Nebulin-deficient mice exhibit shorter thin filament lengths and reduced contractile function in skeletal muscle;Bang;J. Cell Biol.,2006
3. Zebrafish models flex their muscles to shed light on muscular dystrophies;Berger;Dis. Model. Mech.,2012
4. 503unc, a small and muscle-specific zebrafish promoter;Berger;Genesis,2013
5. Dystrophin-deficient zebrafish feature aspects of the Duchenne muscular dystrophy pathology;Berger;Neuromuscul. Disord.,2010
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