1. The Francis Crick Institute, Mill Hill Laboratory, London, NW7 1AA, UK
2. Genome Institute of Singapore, A-STAR, 138672, Singapore
3. MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK
4. Bourn Hall Clinic, Bourn, Cambridge CB23 2TN, UK
5. The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06032, USA