Abstract
Focal adhesions (FAs) are crucial for vascular morphogenesis, but how they influence endothelial cell behaviour in live functioning blood vessels was unknown. In a new paper in Development, Anne Lagendijk and colleagues find that functional FAs are required for endothelial cell rearrangements, in an actin-dependent manner. We caught up with the first author Tevin Chau and corresponding author Anne Lagendijk, a Group Leader at the Institute for Molecular Bioscience (IMB), University of Queensland, Australia, to find out more about their research.
Publisher
The Company of Biologists
Subject
Developmental Biology,Molecular Biology