Meeting report – Mitotic spindle: from living and synthetic systems to theory

Abstract

ABSTRACT Leading scientists from the field of mitotic spindle research gathered from 24–27 March 2019 to participate in the first ‘Mitotic spindle: From living and synthetic systems to theory’ conference. This meeting was held in Split, Croatia, organized by Nenad Pavin (Faculty of Science, University of Zagreb) and Iva Tolić (Ruđer Bošković Institute, Zagreb). Around 75 participants presented the latest advances in mitotic spindle research, ranging from live-cell imaging, in vitro reconstitution experiments and theoretical models of spindle assembly. The meeting successfully created an environment for interesting scientific discussions, initiation of new collaborations and development of fresh ideas. In this report, we will highlight and summarize new data challenging the established models of spindle architecture, advances in spindle reconstitution assays, discovery of new regulators of spindle size and shape as well as theoretical approaches for investigating motor protein function.