Prevalence of non-motor disorders in Parkinson`s disease

Author:

Safonova N. Yu.1,Sapronova M. R.2,Gavrilyuk O A.2,Popova T. E.3,Tappakhov A. A.4

Affiliation:

1. V.M. Bekhterev National Medical Research Centre for Psychiatry and Neurology

2. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University

3. Yakutsk Scientific Centre for Complex Medical Problems

4. M.K. Ammosov North-Eastern Federal University

Abstract

(1) Background: to reveal the prevalence of non-motor disorders in Parkinson’s disease (PD), we analyzed both Russian and international studies on the issue of PD-associated non-motor disorders in Caucasian patients; (2) Methods: We have carried out a search for full-text Englishand Russian-language articles published during the last ten years (from 2010 to 2020) in PubMed, Scopus, Web of Science, Springer, Clinical case, and E-library databases using multiple versions of keywords and their combinations. (3) Results: General prevalence of PD-associated non-motor disorders proved to be high. At the same time, we did not find significant differences between the prevalence of cognitive, affective, or behavioral disorders in PD patients. However, depression was found to be more common in PD patients in the Russian Federation; (4) Conclusions: According to the results of our review, cognitive and affective disorders in PD represent the issues of major concern. 

Publisher

V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology

Reference49 articles.

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2. Tappakhov, A.A.; Popova, T.E.; Nikolayeva, T.Ya.; Shnayder, N.A.; Petrova, M.M. Epidemiology of Parkinson's disease in the world and in Russia. Transbaikal Medical Bulletin 2016, 4, 151-159 (in Russ.).

3. Razdorskaya, V.V.; Voskresenskaya, O.N.; Yudina, G.K. Parkinson's disease in Russia: prevalence and incidence. Saratov Journal of Medical Scientific Research 2016, 3, 379-384 (in Russ.).

4. Ascherio, A.; Schwarzschild, M.A. The epidemiology of Parkinson's disease: risk factors and prevention. The Lancet Neurology. 2016, 15, 12, 1257-1272. doi:10.1016/S1474-4422(16)30230-7.

5. Tysnes, O.B.; Storstein, A. Epidemiology of Parkinson's disease. J Neural Transmission. 2017, 124, 8, 901-905. doi:10.1007/s00702-017-1686-y.

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