Affiliation:
1. Gulbarga University, India
2. Shri Dharmasthala Manjunatheshwara University, Dharwad, India
Abstract
Molecular pharming is a method that combines the use of plants and biotechnological techniques for the production of proteins and bioactive metabolites which are important to support human health and industries. Using genetic engineering techniques, transgenic plants are developed. These plants have applications in the field of agriculture, biofuel, chemical industries, and pharmaceutical industries. These transgenic crop plants with limited facilities can synthesize a large amount of biomass at a low cost, through which a novel source of molecular medicines like plasma proteins, antibodies, vaccines, and growth factors can be isolated. Plant molecular pharming can be used as an alternative to mammalian cells, yeast, or bacterial culture systems for the production of pharmaceutical proteins. This also helps in studying and understanding the mechanism of expression of genes in plants. This chapter deals with the current strategies and approaches used in plant molecular pharming including the strategies, applications, limitations, and biosafety considerations.
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