Affiliation:
1. Universiti Malaya, Malaysia
Abstract
The number of people diagnosed with diabetes mellitus (DM) has risen considerably in recent decades. Diabetes type 1 and 2 are the most frequent types. Type 2 diabetes accounts for 90% of all DM cases globally, making it a 21st-century epidemic. Meanwhile, the side effects and resistance development of routinely used synthetic oral hypoglycemic medications have side effects. It's a need for a safe and less costly substitute. This chapter looks at the anti-diabetic properties of several bioactive compounds derived from plants, such as boldine, bergenin, abietic acid, and myristic acid. This chapter examines the active compounds that can be obtained from plants and their potential use in the treatment of diabetes mellitus, as well as the molecular mechanisms underlying their actions in ameliorating diabetes complications. Consequently, creating novel anti-diabetic oral medications requires a detailed understanding of the mechanisms of action of these phytochemicals.