A Comprehensive Analysis of Findings on Clinical, Radiological, and Histopathological Correlations in Cholesteatoma

Abstract

Cholesteatoma, abnormal growths or keratinized tissue in the middle ear, has many symptoms, making diagnosis difficult. This study examined the complex relationship between clinical, radiological (HRCT), and histological findings in cholesteatoma to improve diagnosis and treatment. The respected Krishna Institute of Medical Sciences and Hospital methodically collected data from 100 suitable patients over 18 months (KIMS). The method included clinical exams, otoendoscopy, HRCT scans, and surgery, followed by a thorough tissue sample analysis. This study found a male propensity for cholesteatoma, peaking in the fourth decade. Discomfortable ear discharge and hearing problems dominated the clinical profile. Clinical investigations and otoendoscopy revealed common abnormalities, with attic retraction pockets accounting for 56% of cases. HRCT scans accurately identified ossicular involvement, indicating the stapes suprastructure in 49% of instances. Histopathological investigations also showed atrophy (95%), acanthosis (90%), and basal cell hyperplasia (90%). (identified in 91 percent of cases).