Affiliation:
1. The Neotia University, India
Abstract
Antimicrobial resistance (AMR) poses a severe global health crisis, claiming over 1.27 million lives worldwide in 2019. In the U.S., more than 2.8 million cases of resistant infections annually result in 35,000 deaths. This chapter delves into the complexities of multi-drug-resistant pathogens, exploring historical instances of resistance and advocating for innovative solutions. It explores alternatives like peptides, gene editing, and unconventional therapies, while addressing challenges in research and the decline of new antibiotic development. Uniquely interdisciplinary, the chapter integrates insights from literature, healthcare reports, and pharmaceutical trends. Meticulously organized, it navigates through challenges and promising innovations, concluding with a call for global action to combat the escalating threat of antibiotic resistance. This knowledge, drawn from literature, case studies, and industry trends, has the potential to significantly advance therapies, safeguard public health, and shape the future of medicine.