In Vitro Antioxidant and In Vitro Cytotoxic Potentials of Ancardium occidentale Linn. Against Hep G2 Cell Lines

Abstract

Cancer is a disease in which there is an uncontrolled multiplication and spread, within the body, of abnormal forms of the body's own cells. The Ethanol extract (EEAO) of Anacardium occidentale Linn was used for In-Vitro anticancer screening against HepG2 cell lines.Preliminary phytochemical analysis of the test drug was carried out and it revealed the presence of Tannin, Terpene, Quinone, Coumarin, Phenol. The results revealed that the extracts have significant Antioxidant potentials. In- vitro cytrotoxic assay such as tryphan blue dye exclusion, MTT and LDH releasing assays were carried out against liver cancer cell line (HepG2). The results showed that the ethanol extract of Anacardium occidentale L. has potent anticancer potentials. From the study it was concluded that the ethanol extract of Anacardium occidentale L. showed significant free radical scavenging and anticancer activity against HepG2 cell line.