Serum Procalcitonin, Ischemia Modified Albumin Biomarkers in Tertiary Hospital Sepsis Patients

Abstract

Sepsis is described as a medical emergency situation due to the body's systemic immunological response to an infection that can lead to end-stage organ dysfunction and even death. Sepsis is one of the major causes of morbidity and mortality in critically morbid patients; however, there is a significant advancement in the understanding of the pathophysiology of this clinical syndrome, hemodynamic monitoring tools, and resuscitation measures. Due to the body's systemic immune reaction to an infection, which may result in end-stage organ malfunction and even death, sepsis is referred to as a medical emergency. It is one of the top ten leading causes of death globally. The epidemiological burden of sepsis is difficult to ascertain globally. Despite tremendous progress in the understanding of the pathogenesis of this clinical illness, hemodynamic monitoring systems, and resuscitation techniques, sepsis continues to be one of the leading causes of morbidity and mortality in critically ill patients.