Abstract
In Chapter 1, the author considers the overall evolving ontological significance of entrepreneurship as a mindset in structural developmental change facilitating both local and rural economic development. Here it is illustrated that entrepreneurship itself is demanding new, non-divisive, non-mechanical developmental approaches to local economic development, in the sense that the current concepts which recognize this approach need to be fostered holistically in order to work well in modern economics. It is further conceived that both in local economic development and entrepreneurship, proposals based on indivisible developmental wholeness offer a much more effective way of approaching the general social-economic and rural reality. In subsequent chapters it will be further shown that rural regions can in fact greatly benefit from these notions. The author indicates that some regions are not able to attract investment and ensure sustainable development while regional and rural development agencies with entrepreneurial thinking offer many available strategic options.