Laboratory Methods for the Diagnosis of SARS-Cov-2-Reference-Cited by-同舟云学术

Laboratory Methods for the Diagnosis of SARS-Cov-2

Published:2022 Issue: Volume: Page:58-77
ISSN:2475-6628
Container-title:Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19
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Author:

Echchakery Mohamed¹,Boussaa Samia²^ORCID,El Mouahid Souad²,Mountassir Maryam³,El Hizazi Said⁴,Klevor Raymond⁵,Keita Ansumana Mohammed⁶,Mouallif Mustapha⁷,Zemrani Yassin⁸,Lamrani Hanchi Asmae⁹,El Baz Soraia³,Alouani Mohamed¹⁰

Affiliation:

1. Higher Institute of Health Sciences, Hassan First University of Settat, Settat, Morocco

2. Higher Institute of Nursing Professions and Health Techniques, Morocco

3. Faculty of Sciences Semlalia, Cadi Ayyad University, Morocco

4. Ecole Supérieure de Technologie, Université Ibn Zohr, Morocco

5. Mohammed VI University Medical Center, Marrakesh, Morocco

6. Arrazi Hospital, Mohammed VI University Teaching Hospital, Morocco

7. Higher Institute of Health Sciences, Hassan First University of Settat, Morocco

8. Arrazi Hospital University Mohammed VI, Morocco

9. Faculty of Medicine and Pharmacy of Marrakech, Cadi Ayyad University, Morocco

10. Faculty of Sciences, University Ibn Zohr, Morocco

Abstract

The coronavirus disease 2019 (COVID-19) which has become the pandemic par excellence of our time places pressure on various aspects of human endeavor and as such requires detailed study to better combat it. However, diagnostic tests were used to provide data on the incidence of COVID-19 and to assess the immune status of infected individuals. The objective of this chapter is to describe the diagnostic methods currently used to identify SARS-CoV-2 infection. Obtaining the first SARS-CoV-2 genome sequence was decisive for the development of molecular diagnostic assays that currently make it possible to diagnose and screen for the Sars-CoV-2 infection. Their uses depend on the target to be detected. Antigenic tests detect the presence of a virus antigen, which usually makes a proteinaceous part of the virus surface. The serology tests detect the presence of antibodies generated against SARS-CoV-2 and are also a relevant tool for epidemiological studies.

Publisher

IGI Global

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