Affiliation:
1. B. S. Abdur Rahaman Crescent Institute of Science and Technology, India
2. ASBASJSM College of Pharmacy, India
Abstract
Colorectal cancer (CRC) is intently connected to the malignancies and mortalities worldwide. Surgery and chemotherapy are the current clinical treatments for CRC. However, new and productive drugs are instantly required to overcome the occurrence of side effects and emergence of drug resistance. Natural products possess apoptogenic activities and anti-cancer effects against CRC as many natural compounds are well tolerated by the patients and do not cause toxic effects even at high doses. The current research aims to display anti-CRC effects of natural products based on chemical structure such as alkaloids, terpenoids, polysaccharides, polyphenols, and unsaturated fatty acids. Furthermore, drugs derived from natural products used clinically for the treatment of CRC are discussed. This work also highlights natural products with marine origin as a candidate drugs for CRC. This work highlights the importance of natural products as promising sources of lead anti-colorectal medicine.