Early-Stage Ovarian Cancer Diagnosis Using Fuzzy Rough Sets with SVM Classification

Abstract

Ovarian cancer is one of the most dangerous cancers among women which have a high rank of the cancers causing death. Ovarian cancer diagnoses are very difficult especially in early-stage because most symptoms associated with ovarian cancer such as Difficulty eating or feeling full quickly, Pelvic or abdominal pain, and Bloating are common and found in Women who do not have ovarian cancer. The CA-125 test is used as a tumor marker, high levels could be a sign of ovarian cancer, but sometimes it is not true because not all women with ovarian cancer have high CA-125 levels, particularly about 20% of ovarian cancers are found at an early stage. In this paper, we try to find the most important rules helping in Early-stage ovarian cancer Diagnosis by evaluating the significance of data between ovarian cancer and the amino acids. Therefore, we propose a Fuzzy Rough feature selection with Support Vector Machine (SVM) classification model. In the pre-processing stage, we use Fuzzy Rough set theory for feature selection. In post-processing stage, we use SVM classification which is a powerful method to get good classification performance. Finally, we compare the output results of the proposed system with other classification technique to guarantee the highest classification performance.