Affiliation:
1. Stanford University, USA
Abstract
The first-line treatment of trigeminal neuralgia can be very effective, but side effects are often difficult for patients to tolerate. This chapter is a guide to the broad selection of medical therapies currently available for the treatment of trigeminal neuralgia which includes oral therapies and other non-surgical methods of treatment such as IV medications, nasal sprays, topical ointments, and injections. The discussion of each treatment includes discussion of its evidence in current literature, its proposed mechanism of action, its dosing and appropriate setting for clinical use, and its side effect profile.
Reference76 articles.
1. Efficacy, safety, and tolerability of duloxetine in idiopathic trigeminal neuralgia.;K.Anand;Journal of the Indian Medical Association,2011
2. Review of a Proposed Mechanism for the Antinociceptive Action of Botulinum Toxin Type A
3. Safety and Efficacy of Oxcarbazepine: Results of Randomized, Double-Blind Trials
4. Beydoun, A., Schmidt, D., & D’Souza, J. (2002). Oxcarbazepine versus carbamazepine in trigeminal neuralgia: a meta-analysis of three double blind comparative trials. Neurology, 58(suppl 3).
5. TRIGEMINAL NEURALGIA: ITS TREATMENT WITH A NEW ANTICONVULSANT DRUG (G-32883)