Today, branding directly affects the growth process for countries, regions, and urban centers. Particularly, a successful branding process, including the framework design and establishment of regulation tools, is necessary and quite important to be able to succeed on recognize and furthermore to enhance the catch-up process, enforce competitiveness level and development. The socio-economic implications from a successful branding are more apparent using some of the main socio-economic variables, such as public investment, employability, and socio-economic regional growth. In this context, the urban and semi-urban centers must clearly define their position in the market through branding and marketing policy. This text attempts to examine the contemporary role of branding and furthermore to examine and analyze the results in the process of development for semi-urban centers in Greece.