Interference Microscopy for Cellular Studies-Reference-Cited by-同舟云学术

Interference Microscopy for Cellular Studies

Published:2009 Issue: Volume: Page:656-672
ISSN:
Container-title:Handbook of Research on Systems Biology Applications in Medicine
language:
Short-container-title:

Author:

Brazhe Alexey R.¹,Brazhe Nadezda A.¹,Pavlov Alexey N.²,Maksimov Georgy V.³

Affiliation:

1. Technical University of Denmark, Denmark and Moscow State University, Russia

2. Saratov State University, Russia

3. Moscow State University, Russia

Abstract

This chapter describes the application of interference microscopy and double-wavelet analysis to noninvasive study of cell structure and function. We present different techniques of phase and interference microscopy and discuss how variations in the intrinsic optical properties of a cell can be related to the intracellular processes. Particular emphasis is given to the newly developed phase modulation laser interference microscope. We show how this setup, combined with wavelet analysis of the obtained data series, can be applied to live cell imaging to investigate the rhythmic intracellular processes and their mutual interactions. We hope that the discussion will contribute to the understanding and learning of new methods for non-invasive investigation of intracellular processes.

Publisher

IGI Global

Reference32 articles.

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