In the present study, the effect of Soil Structure Interaction (SSI) of low, mid and high rise (G+1, G+4, and G+9 storey) buildings has been evaluated by nonlinear dynamic analysis using three-dimensional finite element method. Three types of uniform soils namely hard soil, medium soil and soft soil have been considered for the present analysis. These buildings have been subjected to Loma Prieta (1989) earthquake motion and Denali (2002) earthquake motion as near field and far field earthquake motions respectively under the above mentioned soil conditions. From the analysis, the horizontal displacements and percentage of drifts have been determined of all the storeys of the buildings under the above mentioned three soil conditions and the two earthquakes. Further, for all the cases fragility curves have been computed. Furthermore, on the basis of the fragility curve and seismic hazard curve of a region, Reliability Index (RI) have also been developed.