INVESTIGATION OF SOME BIOLOGICAL PROPERTIES OF PROPOLIS IN HAWTHORN VINEGAR EXTRACT

Abstract

With the determination of the biological activity of different components in the chemistry of propolis, its importance has increased day by day and its use in the field of integrative medicine has become widespread. Propolis is not used in its crude form due to its physical properties, it have to be extracted. The type of solvent used in the extraction process is very important for the efficiency of the biological activity of propolis. Solvents commonly used in propolis extraction; are water, ethanol and methanol. Besides being very easy to extract propolis components using ethanol; extraction of propolis with ethanol creates a usage limit for children, pregnant women and muslim people that don't use alcohol. The limited use of ethanol and the fact that it has some harm to health have led researchers to search for different types of solvents. As a result of these researches, vegetable oils and various vinegars have started to be in the literature as an alternative solvent. In our study, the vinegar of hawthorn fruit, which is rich in flavonoids and has been used in integrative medicine for many years, was used in the extraction of propolis. Solubility of propolis with hawthorn vinegar, physicochemical properties (pH, titratable acidity, ºbrix and color) and bioactive properties (phenolic, flavonoid contents and antioxidant activities) in terms of researched. As a result of the research, it was observed that propolis increased the bioactive properties of hawthorn vinegar. As a result of the research, it was observed that propolis increased the bioactive properties of hawthorn vinegar. It is thought that propolisadded hawthorn vinegar will provide functionality in dishes where vinegar is used today, in salads, and even in foodstuffs such as brine and pickles.