Diabetic Ketoacidosis, Hypertriglyceridemia and Abdominal Pain due to Acute Pancreatitis Complicated by Non-immune Haemolytic Anaemia

Author:

Monica Joustra 1,Janneke Raidt 1,Florens Droog 2,Thiemo Veneman 2

Affiliation:

1. Department of Internal Medicine, Ziekenhuisgroep Twente (Hospital Group Twente), Almelo, The Netherlands

2. Department of Intensive Care Medicine, Ziekenhuisgroep Twente (Hospital Group Twente), Almelo, The Netherlands

Abstract

The triad of diabetic ketoacidosis, acute pancreatitis and hypertriglyceridemia is a rare phenomenon, with mortality rates of up to 80%. A unique characteristic of the described case is the co-occurrence of non-immune haemolytic anaemia (NIHA) with the complex triad. It is suggested that this presentation is secondary to hyperlipidemia which leads to increased fragility of erythrocytes due to destabilization of red cell membranes. Supportive treatment with intravenous insulin and blood transfusions is the cornerstone of treatment.

Publisher

SMC Media

Subject

Internal Medicine

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