Poor oocyte quality as a cause of embryo fragmentation in IVF program: clinical case report

Abstract

High degree of embryo fragmentation correlates with absence of implantation in IVF programs. The aim of the work was to determine the most probable cause of embryo fragmentation and ineffective in vitro fertilization (IVF) program on the example of a specific clinical situation and based on the analysis of literature data. In contrast to the common form of infertility, associated with the absence of ovulation and constituting 35-40% in the structure of infertility factors, , this clinical situation is unusual due to the fact that pregnancy as a result of repeated IVF programs did not occur due to the production of fragmented embryos with a preserved ovarian reserve and the exclusion of other infertility factors. The successful solution of reproductive problems in this couple is obviously associated with the use of the oocyte donation program.