Abstract
"Metaplasia” is a concept of differentiated cells and tissues transformation that has been discussed since the second half of the19th century. The issues of the research were the essence, mechanisms and role in histogenetic and pathological process. The aim of this review is an attempt to trace and analyse the evolution of ideas about cells and tissues transformation possibilities beginning from the R. Virchow observations (1958). Also there is a need to correlate them with the modern understanding of the issues of the of opportunities in cell differentiation and the underlying pathological processes.
Subject
Transplantation,Cell Biology,Molecular Biology,Biomedical Engineering,Surgery,Biotechnology
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