Neonatal cortical hyperostosis secondary to prolonged use of prostaglandin E1 in a patient with pulmonary atresia
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Published:2016-01-01
Issue:1
Volume:22
Page:51-53
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ISSN:2564-7040
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Container-title:European Journal of Therapeutics
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language:
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Short-container-title:Eur J Ther
Author:
Doğan Nazan Neslihan,Dilli Dilek,Pala Akdoğan Melek,Örün Utku Arman,Aydın Hakan,Zencircioğlu Ayşegül
Abstract
Pulmonary atresia is a rare congenital cardiac malformation. The newborns with this anomaly are ductus dependent to maintain a continuous and adequate pulmonary blood fl ow. As spontaneous closure of the ductus is expected after few hours or days after birth, the patency of ductus should be provided by prostaglandin E1 (PGE1) while the patient is awaiting cardiosurgical intervention. PGE1 infusion is usually applied for a short time period. However, in some circumstances, the infusion duration may extend from weeks to months. Long term PGE1 infusions may produce several adverse effects. In this report, we presented a case of newborn with pulmonary atresia who developed cortical hyperostosis secondary to prolonged use of PGE1.
Publisher
Pera Publishing