Valuation of Cavities in the Lungs Among HIV/TB Patients-Reference-Cited by-同舟云学术

Valuation of Cavities in the Lungs Among HIV/TB Patients

Published:2021-08-25 Issue:4 Volume: Page:22-33
ISSN:2713-0118
Container-title:Radiology - Practice
language:
Short-container-title:jour

Author:

Masterova I. Yu.¹^ORCID,Degtyareva S. Yu.²^ORCID,Narkevich A. N.³^ORCID,Shlykova L. A.⁴^ORCID,Zaitseva E. V.⁵^ORCID,Gavrilov P. V.⁵^ORCID

Affiliation:

1. St. Petersburg Research Institute of Phthisiopulmonology, Ministry of Healthcare of Russia; Medical and Sanitary unit No. 78 of the Federal Penitentiary Service of Russia, Tuberculosis Hospital No. 1, Villoz City, Lomonosov District, Leningrad Region

2. Peoples’ Friendship University of Russia

3. Krasnoyarsk State Medical University named after Professor V. F. Voino-Yasenetsky, Ministry of Healthcare of Russia

4. Medical and Sanitary unit No. 78 of the Federal Penitentiary Service of Russia, Tuberculosis Hospital No. 1, Villoz City, Lomonosov District, Leningrad Region

5. St. Petersburg Research Institute of Phthisiopulmonology, Ministry of Healthcare of Russia

Abstract

Early diagnosis of respiratory tuberculosis among HIV-infected patients improves the prognosis of recovery and reduces mortality. The emergence of cavities is one of the patterns of the progression of pulmonary tuberculosis. The article analyzes the results of examination of HIV-infected tuberculosis patients with cavities. We estimate the data of anamnesis, the disease clinic and immune status. The retrospective study included patients of the Leningrad region with HIV/TB with early respiratory tuberculosis from 2014 to 2016 (n = 852). We identified a clear relationship between chemoprophylaxis and antiretroviral therapy on developing tuberculosis non-cavity, but no direct relationship was found with widespread or disseminated TB. We also obtained a significantly relationship between the bacterial excretion and the detection of destruction in the lung tissue on the background a pronounced decrease in the immune status (CD4 100 cells/μl or less). There are statistically significant decreases in the frequency of cavities of respiratory tuberculosis and the proportion of etiologically verified cases is in case in the suppression of immunity (CD4 100 cells/μl or less). However, the relationship between early mortality from tuberculosis (during the first year) and pulmonary tuberculosis with cavities was not obtained.

Publisher

Central Research Institute of Radiation Diagnostics

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