Evaluation of the Efficacy of Neoadjuvant Radiation Twice a Day Fractionation Therapy in Patients with Resectable Pancreatic Head Cancer

Author:

Korytova L. I.1ORCID,Sklyar D. A.1ORCID,Vlasova E. V.1ORCID,Pavlovskiy A. V.1ORCID,Polikarpov A. A.1ORCID,Moiseenko E. V.1ORCID,Korytov O. V.1ORCID

Affiliation:

1. Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. Granov of the Ministry of Health of the Russian Federation

Abstract

The coronavirus of severe acute respiratory syndrome-2 (SARS-CoV-2) and the coronavirus infection caused by it, along with damage to the respiratory system, can lead to disorders of the central and peripheral nervous system. The article presents literature data and own observations of neurological disorders in patients with coronavirus disease in the superacute period. Pronounced neurological disorders are mainly observed in severe coronavirus disease and include acute ischemic stroke, subcortical micro- and macro— bleeding, acute necrotizing encephalopathy, Guillain-Barre syndrome. Factors potentially complicating the course of coronavirus disease and contributing to the development of neurological complications are hypertension, diabetes mellitus, chronic diseases of the heart and respiratory system. Based on existing publications and our own observations, we have systematized information about the relationship between coronavirus disease and neurological disorders, about possible factors contributing to the occurrence of stroke. The possibilities of using chest MSCT as the only method of radiation diagnostics for the early detection of viral pneumonia in patients receiving emergency and emergency care at the regional vascular center of BUZOO «GC BSMP No. 1» are considered. The use of this method, in the ultra-acute period of acute ischemic stroke, during the first 40 minutes from the moment of admission, can significantly reduce the time of diagnosis and mortality in patients with acute ischemic stroke and viral pneumonia.

Publisher

Central Research Institute of Radiation Diagnostics

Reference17 articles.

1. Granov D. A., Polikarpov A. A., Pavlovskij A. V., Moiseenko V. E., Popov S. A. Evaluation of intra-arterial chemotherapy safety by using of gemcitabine and oxaliplatin in combined treatment of pancreatic head adenocarcinoma. Annals of HPB Surgery. 2017. V. 22. No. 2. P. 54–59 (in Russian).

2. Kaprin A. D. The state of cancer care for the population of Russia in 2020. P. Hertsen MORI. Moscow. 2021. P. 239.

3. Korytova L. I. et al. Possibilities of conformal radiotherapy in the treatment of patients with locally advanced pancreatic cancer. Rossijskij bioterapevticheskij zhurnal. 2017. V. 16. No. s1. P. 44–45 (in Russian).

4. Lushnikov E. F. et al. Therapeutic pathomorphosis of tumors. Pathological diagnosis of human tumors Мoscow: Medicina, 1993. P. 560 (in Russian).

5. Pavlovskij A. V. et al. Influence of perioperative intraarterial selective chemotherapy on terms of recurrent ductal adenocarcinoma of the pancreatic head after pancreaticoduodenectomy. Annals of HPB Surgery. 2018. Т. 23. No. 3. С. 14–22 (in Russian).

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