Affiliation:
1. Johns Hopkins University School of Medicine and The Department of Cognitive Science
2. Johns Hopkins University Department of Cognitive Science
3. Johns Hopkins University School of Medicine, Department of Psychiatry
Abstract
This longitudinal study of two patients with Alzheimer's disease (AD), on 12 experimental tasks, was designed to identify a measure of cognitive decline in AD patients that would be sensitive to change over short periods (weeks), resistant to practice (repeated testing over a few weeks), and predictive of change over longer periods on standardized tests. During the periods of frequent testing, both patients improved on most tasks, but performance on the tasks of spelling words and spelling pseudowords declined in both patients during periods when they deteriorated on standardized testing. It is concluded that simple spelling tasks may provide a good baseline of the rate of cognitive decline to identify effects of intervention, at least in some AD patients.
Publisher
American Speech Language Hearing Association
Subject
Speech and Hearing,Linguistics and Language,Developmental and Educational Psychology,Otorhinolaryngology
Reference15 articles.
1. Neuropsychological heterogeneity in mild Alzheimer’s disease;Binetti G.;Dementia,1993
2. The prognosis in Alzheimer’s disease: ‘How far’ rather than ‘how fast’ predicts the course;Drachman D.;Archives of Neurology,1990
3. Mini-mental state”: A practical method for grading the mental state of patients for the clinician;Folstein M.;Journal of Psychiatric Research,1975
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献