Author:
Thirunarayanan Ganesamoorthy
Abstract
Some (4-bromo-1-naphthyl)-(3-(substituted phenyl) bicyclo[2.2.1]hept-5-en-2-yl) methyl ketones were synthesized by fly-ash catalyzed environmentally benign Diels-Alder [4+2] cycloaddition reaction of 4-bromo-1-naphthyl chalcones and cyclopentadiene in water medium. In this reaction, the obtained yield was more than 60%. The synthesized methanones were characterized by their physical constants, microanalysis, infrared, nuclear magnetic resonance and mass spectroscopic data. The antibacterial and antifungal activities of these ketones were evaluated by the disc diffusion-zone of inhibition and two-fold serial-dilution-minimum inhibitory concentration of their corresponding bacterial and fungal strains using the Bauer-Kirby method. The antioxidant activities of these methanones were measured using the diphenyl picryl hydrazyl (DPPH) radical scavenging activity method.
Publisher
Society of Chemists and Technologists of Macedonia
Subject
General Chemical Engineering,General Chemistry
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献